protein AND (interaction OR binding)
20091224
1019446
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors
on damaged chromosomes.
Bekker-Jensen S, Danielsen JR, Fugger K, Gromova I, Nerstedt
A, Bartek J, Lukas J, Mailand N.
Nat Cell Biol. 2010 Jan;12(1):80-6. Epub 2009
Dec 20.PMID: 20023648
ユビキチン化とタンパク質間相互作用
Target
identification using drug affinity responsive target stability (DARTS).
Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S,
Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J,
Herschman HR, Clardy J, Clarke CF, Huang J.
Proc
Natl Acad Sci U S A. 2009 Dec 7. [Epub ahead of print]PMID: 19995983
NOTCH
AND THE SKELETON.
Zanotti S, Canalis E.
Mol Cell Biol. 2009 Dec 7. [Epub
ahead of print]PMID: 19995916
Rational
design of a structural and functional nitric oxide reductase.
Yeung N, Lin YW, Gao YG, Zhao X, Russell BS, Lei L, Miner KD,
Robinson H, Lu Y.
Nature. 2009
Nov 25. [Epub ahead of print]PMID: 19940850
酵素をデザインする
HIV-1
Gag-specific immunity induced by a lentivector-based vaccine directed to
dendritic cells.
Dai B, Yang L, Yang H, Hu B, Baltimore D, Wang P.
Proc
Natl Acad Sci U S A. 2009 Nov 16.
PMID: 19918062
レンチウィルスベクターのワクチン
RNA
recognition by the embryonic cell fate determinant and germline totipotency
factor MEX-3.
Pagano JM, Farley BM, Essien KI, Ryder SP.
Proc
Natl Acad Sci U S A. 2009 Nov 13.
PMID: 19915141
MEX-3が作用するRNAのコンセンサス配列
A
type I-secreted, sulfated peptide triggers XA21-mediated innate
immunity.
Lee SW, Han SW, Sririyanum M, Park CJ, Seo YS, Ronald PC.
Science. 2009 Nov
6;326(5954):850-3.
PMID: 19892983
バクテリアから獲得した、コメの免疫促進ペプチド
Mitotic
chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human
EBNA1-binding protein 2 (EBP2).
Kapur Nayyar V, Shire K, Frappier L.
J Cell Sci. 2009 Nov 3.
PMID: 19887584
体細胞分裂の際のタンパク質間相互作用
Evolution of biomolecular networks - lessons from metabolic and protein
interactions
.Yamada T, Bork P.
Nat Rev Mol Cell Biol.
2009 Nov;10(11):791-803.PMID: 19851337
レビュー
Dynamics
and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC)
complex proteins.
Ostlund C, Folker ES, Choi JC, Gomes ER, Gundersen GG, Worman
HJ.
J Cell Sci. 2009 Oct 20. [Epub ahead of
print]PMID: 19843581
核内骨格、細胞内骨格
Computer-aided
design of functional protein interactions.
Mandell DJ, Kortemme T.
Nat Chem Biol. 2009
Nov;5(11):797-807.PMID: 19841629
コンピューターで相互作用を予測
Histone H1 binding is inhibited by histone variant
H3.3.
Braunschweig U, Hogan GJ, Pagie L, van Steensel B.
EMBO J. 2009 Oct 15.
PMID: 19834459
ヒストンH1とH3.3が競合している
Human DNA methylomes at base resolution show
widespread epigenomic differences.
Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G,
Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget
J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, Ecker JR.
Nature. 2009 Oct 14.
[Epub ahead of print]
PMID: 19829295
一塩基単位で、ゲノム中のシトシンのメチル化を解析
Separation and detection of large phosphoproteins
using Phos-tag SDS-PAGE.
Kinoshita E, Kinoshita-Kikuta E, Koike T.
Nat
Protoc. 2009;4(10):1513-21. Epub 2009 Sep 24.
PMID: 19798084
リン酸化たんぱく質の分離と同定
Cooperative binding of two acetylation marks on a
histone tail by a single bromodomain.
Moriniere J, Rousseaux S, Steuerwald U, Soler-Lopez M, Curtet
S, Vitte AL, Govin J, Gaucher J, Sadoul K, Hart DJ, Krijgsveld J, Khochbin S,
Muller CW, Petosa C.
Nature. 2009 Oct
1;461(7264):664-8.
PMID: 19794495
ヒストンの修飾と転写開始
Histone crosstalk between H3S10ph and H4K16ac
generates a histone code that mediates transcription elongation.
Zippo A, Serafini R, Rocchigiani M, Pennacchini S, Krepelova A,
Oliviero S.
Cell. 2009 Sep
18;138(6):1122-36.
PMID: 19766566
ヒストンと転写との相互作用
A Genome-wide RNAi Screen for Modifiers of the
Circadian Clock in Human Cells.
Zhang EE, Liu AC, Hirota T, Miraglia LJ, Welch G, Pongsawakul
PY, Liu X, Atwood A, Huss JW 3rd, Janes J, Su AI, Hogenesch JB, Kay SA.
Cell. 2009 Sep 16.
PMID: 19765810
サーカディアンリズムを変える遺伝子をRNAiでスクリーニングし、相互作用を推定
Proteomics strategy for quantitative protein
interaction profiling in cell extracts.
Sharma K, Weber C, Bairlein M, Greff Z, Keri G, Cox J, Olsen
JV, Daub H.
Nat
Methods. 2009 Sep 13.
PMID: 19749761
プロトコール
In
vivo expression and purification of aptamer-tagged small RNA regulators.
Said N, Rieder R, Hurwitz R, Deckert J, Urlaub H, Vogel J.
Nucleic
Acids Res. 2009 Sep 2
PMID: 19726584
スモールRNA結合タンパク質群を精製
Making
the right connections: biological networks in the light of evolution.
Knight CG, Pinney JW.
Bioessays. 2009 Aug 31.
PMID: 19722181
タンパク質間相互作用の進化
MCM10
mediates RECQ4 association with MCM2-7 helicase complex during DNA
replication.
Xu X, Rochette PJ, Feyissa EA, Su TV, Liu Y.
EMBO J. 2009 Aug 20.
PMID: 19696745
複製に関与するタンパク質複合体
Direct
observation of the binding state of the kinesin head to the microtubule.
Guydosh NR, Block SM.
Nature. 2009 Aug 19.
PMID: 19693012
キネシン一分子の動きを観察
A
small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase
A inhibits growth of Ewing's sarcoma.
Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg
JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky
JA.
Nat Med.
2009 Jul;15(7):750-6. Epub 2009 Jul 5.
PMID: 19584866
タンパク質複合体と低分子との結合
Ubiquitin
degradation with its substrate provides clues to proteasome regulation.
Shabek N, Herman-Bachinsky Y, Ciechanover A.
Proc
Natl Acad Sci U S A. 2009 Jul 6.
PMID: 19581590
ユビキチンとプロテアゾームによるタンパク質分解
Conditional
and reversible disruption of essential herpesvirus proteins.
Glas M, Busche A, Wagner K, Messerle M, Borst EM.
Nat
Methods. 2009 Jul 5.
PMID: 19578384
ヘルペスウィルスのたんぱく質を不安定化させる
Reversible
acetylation of the chromatin remodelling complex NoRC is required for non-coding
RNA-dependent silencing.
Zhou Y, Schmitz KM, Mayer C, Yuan X, Akhtar A, Grummt I.
Nat Cell
Biol. 2009 Jul 5.
PMID: 19578370
クロモゾームタンパク質のアセチル化とncRNA
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