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miRNA 20081217


3863

MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc.
Aguda BD, Kim Y, Piper-Hunter MG, Friedman A, Marsh CB.
Proc Natl Acad Sci U S A. 2008 Dec 9.
PMID: 19066217
miRNAと発がん

Right into the heart of microRNA-133a.
Meder B, Katus HA, Rottbauer W.
Genes Dev. 2008 Dec 1;22(23):3227-31.
PMID: 19056878
miRNAと心臓の形成


Twist-1 regulates the miR-199a/214 cluster during development.
Lee YB, Bantounas I, Lee DY, Phylactou L, Caldwell MA, Uney JB.
Nucleic Acids Res. 2008 Nov 23.
PMID: 19029138
miRNAを調節する因子

A Human snoRNA with MicroRNA-Like Functions.
Ender C, Krek A, Friedlander MR, Beitzinger M, Weinmann L, Chen W, Pfeffer S, Rajewsky N, Meister G.
Mol Cell. 2008 Nov 21;32(4):519-28.
PMID: 19026782
miRNA-like スモールRNA


Kelly EJ, Hadac EM, Greiner S, Russell SJ.
Engineering microRNA responsiveness to decrease virus pathogenicity.
Nat Med. 2008 Nov;14(11):1278-83. Epub 2008 Oct 26.
PMID: 18953352
miRNAを調節して、ウィルス感染を調節

Chang YM, Juan HF, Lee TY, Chang YY, Yeh YM, Li WH, Shih AC.
Prediction of human miRNAs using tissue-selective motifs in 3' UTRs.
Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17061-6. Epub 2008 Oct 24.
PMID: 18952845
組織特異的miRNAの特徴


Flynt AS, Lai EC.
Biological principles of microRNA-mediated regulation: shared themes amid diversity
.Nat Rev Genet. 2008 Nov;9(11):831-42.
PMID: 18852696
レビュー

Kim DH, Satrom P, Snove O Jr, Rossi JJ.
MicroRNA-directed transcriptional gene silencing in mammalian cells.
Proc Natl Acad Sci U S A. 2008 Oct
PMID: 18852463
転写を抑制するmiRNAもある

Ambros V.
The evolution of our thinking about microRNAs.
Nat Med. 2008 Oct;14(10):1036-40. No abstract available.
PMID: 18841144


Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, King N, Degnan BM, Rokhsar DS, Bartel DP.
Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals.
Nature. 2008 Oct 1.
PMID: 18830242
miRNAとpiRNAの進化

Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I.
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.
Nature. 2008 Sep 17.
PMID: 18806776
分化に関与するmiRNA

Horwich MD, Zamore PD.
Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells.
Nat Protoc. 2008;3(10):1537-49.
PMID: 18802435
miRNAの機能をブロックするアンチセンスの設計

Ramachandran V, Chen X.
Degradation of microRNAs by a family of exoribonucleases in Arabidopsis.
Science. 2008 Sep 12;321(5895):1490-2.
PMID: 18787168
miRNAの分解

Yekta S, Tabin CJ, Bartel DP.
MicroRNAs in the Hox network: an apparent link to posterior prevalence.
Nat Rev Genet. 2008 Oct;9(10):789-96.
PMID: 18781158
発生をコントロールするmiRNA


Bhat B, Esau C, Davis S, Propp S, Kinberger G, Gaus H, Freier S, Swayze EE, Bennett CF.

2'-O-Methoxyethyl/2'-Fluoro Modified Oligonucleotides Result in More Potent Inhibition of micro RNA-122 in Vivo: A Target implicatedin HCV Replication.
Nucleic Acids Symp Ser (Oxf). 2008;(52):69.
PMID: 18776257


Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A.
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.
EMBO J. 2008 Aug 28. [Epub ahead of print]
PMID: 18756266

Foekens JA, Sieuwerts AM, Smid M, Look MP, de Weerd V, Boersma AW, Klijn JG, Wiemer EA, Martens JW.
Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer.
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13021-6. Epub 2008 Aug 28.
PMID: 18755890

Pichiorri F, Suh SS, Ladetto M, Kuehl M, Palumbo T, Drandi D, Taccioli C, Zanesi N, Alder H, Hagan JP, Munker R, Volinia S, Boccadoro M, Garzon R, Palumbo A, Aqeilan RI, Croce CM.
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis.
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12885-90. Epub 2008 Aug 26.
PMID: 18728182

Grosshans H, Filipowicz W.
Proteomics joins the search for microRNA targets.
Cell. 2008 Aug 22;134(4):560-2.
Widespread changes in protein synthesis induced by microRNAs.
Nature. 2008 Jul 30. [Epub ahead of print]
PMID: 18668040

Baek D, Villen J, Shin C, Camargo FD, Gygi SP, Bartel DP.
The impact of microRNAs on protein output.
Nature. 2008 Jul 30. [Epub ahead of print]
MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs.
Nature. 2008 Jul 2.
PMID: 18596690

Kong YW, Cannell IG, de Moor CH, Hill K, Garside PG, Hamilton TL, Meijer HA, Dobbyn HC, Stoneley M, Spriggs KA, Willis AE, Bushell M.
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene.
Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8866-71. Epub 2008 Jun 25.
PMID: 18579786

Sandberg R, Neilson JR, Sarma A, Sharp PA, Burge CB.
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.
Science. 2008 Jun 20;320(5883):1643-7.
PMID: 18566288



Kumar MS, Lu J, Mercer KL, Golub TR, Jacks T.
Impaired microRNA processing enhances cellular transformation and tumorigenesis.
Nat Genet. 2007 Apr 1; [Epub ahead of print]
PMID: 17401365
miRNAの発現減少とがん化との相関

Niwa R, Slack FJ.
The evolution of animal microRNA function.
Curr Opin Genet Dev. 2007 Feb 19; [Epub ahead of print]
PMID: 17317150


Fahlgren N, Howell MD, Kasschau KD, Chapman EJ, Sullivan CM, Cumbie JS, Givan SA, Law TF, Grant SR, Dangl JL, Carrington JC.
High-Throughput Sequencing of Arabidopsis microRNAs: Evidence for Frequent Birth and Death of MIRNA Genes.
PLoS ONE. 2007 Feb 14;2:e219.
PMID: 17299599


Chen K, Rajewsky N.
The evolution of gene regulation by transcription factors and microRNAs.
Nat Rev Genet. 2007 Feb;8(2):93-103.
PMID: 17230196
miRNAの進化

Arteaga-Vazquez M, Caballero-Perez J, Vielle-Calzada JP.
A Family of MicroRNAs Present in Plants and Animals.
Plant Cell. 2006 Dec 22; [Epub ahead of print]
PMID: 17189346

動物と植物に共通のmiRNA。想像するに、miRNAの起源はウィルスなのか、進化の過程でどのようなはたらきをしているのか、外来のウィルス様配列RNAが、生物の遺伝子発現を調節したのか、今後miRNA配列の進化と遺伝子発現調節機構の進化についても注目です。

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